Diagram of bird flu. Some isolates of influenza a virus cause severe disease both in domestic poultry and rarely in humans. Birds bird flu graphic 3. The particular structure of the influenza virus genome and function of its viral proteins enable antigenic drift and antigenic shift. H5n1 avian bird flu.
In the united states alone approximately 25 to 50 million people contract influenza each year. Artwork above showing avian influenza viruses h5n1 shown in green emerging from birds and mixing with other strains blue of influenza virus creating the potential for a new strain red yellow which can pass easily from person to person thereby creating the potential for a pandemic. H7n9 virus origin diagram cdc pdf 129 kb 1 page high resolution 1 mb. The influenza viruses are characterized by segmented negative strand rna genomes requiring an rna dependent rna polymerase of viral origin for replication.
It is enzootic maintained in the population in many bird populations especially in southeast asia. However some infections have been identified where direct contact was not known to have occurred. As the spray of droplets in the sneeze emerges from the nose of the sufferer it aerosolises meaning that the droplets are so small that they dry almost instantaneously on contact with the air. Illness in people has ranged from mild to severe.
Caused outbreaks in domestic poultry in parts of asia and the middle east. A bird adapted strain of h5n1 called hpai ah5n1 for highly pathogenic avian influenza virus of type a of subtype h5n1 is the highly pathogenic causative agent of h5n1 flu commonly known as avian influenza bird flu. Above image measures 500 pixels across but the original image is 5657 x. In some asian countries it is even a custom for humans to consume raw poultry blood.
The influenza flu virus next to the common cold influenza or the flu is perhaps the most familiar respiratory infection in the world. Influenza a virus causes influenza in birds and some mammals and is the only species of the genus alphainfluenzavirus of the virus family orthomyxoviridae. Human infection with h5n1 is rare nearly 650 cases of human cases of h5n1 have been reported from 15 countries since 2003. This diagram depicts the origins of the h7n9 virus from china and shows how the viruss genes came from other influenza viruses in birds.
Strains of all subtypes of influenza a virus have been isolated from wild birds although disease is uncommon. But flu virus is resistant to this drying process.